258.Natural killer cell activity in the adult rat testis
نویسندگان
چکیده
منابع مشابه
Developing and Adult Rat Testis
23 Iron is essential for male fertility and disruptions in iron balance lead to impairment of testicular 24 function. The divalent metal transporter DMT1 is a key modulator of transferrin and non-transferrin 25 bound iron homeostasis. As a first step in determining the role of DMT1 in the testis, we have 26 determined the pattern of DMT1 expression in the developing and adult rat testis. Northe...
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The Sertoli cells are critical regulators of testis differentiation and development. In the adult, however, their known function is restricted largely to maintenance of spermatogenesis. To determine whether the Sertoli cells regulate other aspects of adult testis biology we have used a novel transgenic mouse model in which Amh-Cre induces expression of the receptor for Diphtheria toxin (iDTR) s...
متن کاملEffects of Estradiol and Methoxychlor on Leydig Cell Regeneration in the Adult Rat Testis
The objective of the present study is to determine whether methoxychlor (MXC) exposure in adulthood affects rat Leydig cell regeneration and to compare its effects with estradiol (E2). Adult 90-day-old male Sprague-Dawley rats received ethane dimethane sulfonate (EDS) to eliminate the adult Leydig cell population. Subsequently, rats were randomly assigned to four groups and gavaged with corn oi...
متن کاملA Short-Term Exposure to Tributyltin Blocks Leydig Cell Regeneration in the Adult Rat Testis
Background: Tributyltin (TBT) is widely used as an antifouling agent that may cause reproductive toxicity. The mechanism of TBT on Leydig cell development is still unknown. The objective of the present study was to investigate whether a brief exposure to low doses of TBT permanently affects Leydig cell development and to clarify the underlying mechanism. Methods: Adult male Sprague Dawley rats ...
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ژورنال
عنوان ژورنال: Reproduction, Fertility and Development
سال: 2004
ISSN: 1031-3613
DOI: 10.1071/srb04abs258